Section outline

  • Electron micrograph shows a long, thin chromosome that has a banding pattern

    Now that you understand meiosis, you have the fundamentals necessary to discuss Sutton's Chromosomal Theory of Inheritance and genetic linkage.  By understanding genetic linkage and a new concept that is introduced, crossing over, we will then explore genetic disorders, some of which you may be familiar with.  This chapter will also present a karyotype to give you a visual understanding of chromosomes and the concepts introduced.


    Image from Biology 2e from OpenStax, licensed under Creative Commons Attribution License v4.0 with the image credit: modification of work by “LPLT”/Wikimedia Commons; scale-bar data from Matt Russell



    Upon completion of this module, you will be able to:
    1. Discuss Sutton’s Chromosomal Theory of Inheritance (Course Outcome #4)
    2. Describe genetic linkage (Course Outcome #4)
    3. Explain the process of homologous recombination, or crossing over (Course Outcome #4)
    4. Describe how a karyogram is created (Course Outcome #4)
    5. Explain how nondisjunction leads to disorders in chromosome number (Course Outcome #4)
    6. Compare disorders that aneuploidy causes (Course Outcome #4)
    7. Describe how errors in chromosome structure occur through inversions and translocations (Course Outcome #4)

    To achieve these objectives: 

    1. Read the Module 12 Introduction 
    2. Read and view the materials in the Module 12 Pressbooks book, embedded below by section for the chapter titled Modern Understandings of Inheritance
    3. Complete the assignment and discussion forum post and response.


    This module's lab activity is included as well, to occur in the lab class. Slides are available to accompany the class lecture.

    Module Pressbooks Resources and Activities

    You will find the following resources and activities in this module at the Pressbooks website. Click on the links below to access or complete each item.

Accessibility

Background Colour Background Colour

Font Face Font Face

Font Kerning Font Kerning

Font Size Font Size

1

Image Visibility Image Visibility

Letter Spacing Letter Spacing

0

Line Height Line Height

1.2

Link Highlight Link Highlight

Text Colour Text Colour